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Androgen Receptor and its Splice Variant, AR-V7, Differentially Regulate FOXA1 Sensitive Genes in LNCaP Prostate Cancer Cells

Prostate cancer (PCa) is an androgen-dependent disease, and tumors that are resistant to androgen ablation therapy often remain androgen receptor (AR) dependent. Among the contributors to castration-resistant PCa are AR splice variants that lack the ligand-binding domain (LBD). Instead, they have sm...

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Detalhes bibliográficos
Main Authors: Krause, William C., Shafi, Ayesha A., Nakka, Manjula, Weigel, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160387/
https://ncbi.nlm.nih.gov/pubmed/25008967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.06.013
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