Functional Dissection of Eyes absent Reveals New Modes of Regulation within the Retinal Determination Gene Network

Por Silver, Serena J., Davies, Erin L., Doyon, Laura, Rebay, Ilaria
Publicado em 2003

Functional screening identifies miR-315 as a potent activator of Wingless signaling

Por Silver, Serena J., Hagen, Joshua W., Okamura, Katsutomo, Perrimon, Norbert, Lai, Eric C.
Publicado em 2007

Using Drosophila to Decipher How Mutations Associated With Human Branchio-Oto-Renal Syndrome and Optical Defects Compromise the Protein Tyrosine Phosphatase and Transcriptional Fun...

Por Mutsuddi, Mousumi, Chaffee, Benjamin, Cassidy, Justin, Silver, Serena J., Tootle, Tina L., Rebay, Ilaria
Publicado em 2005

Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening

Por Griner, Lesley Mathews, Gampa, Kalyani, Do, Toan, Nguyen, Huyen, Farley, David, Hogan, Christopher J., Auld, Douglas S., Silver, Serena J.
Publicado no J Vis Exp (2018)

Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning

Por Jones, Thouis R., Carpenter, Anne E., Lamprecht, Michael R., Moffat, Jason, Silver, Serena J., Grenier, Jennifer K., Castoreno, Adam B., Eggert, Ulrike S., Root, David E., Golland, Polina, Sabatini, David M.
Publicado em 2009

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

Por Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Publicado em 2010

A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection

Por Shapira, Sagi D., Gat-Viks, Irit, Shum, Bennett O.V., Dricot, Amelie, Degrace, Marciela M., Liguo, Wu, Gupta, Piyush B., Hao, Tong, Silver, Serena J., Root, David E., Hill, David E., Regev, Aviv, Hacohen, Nir
Publicado em 2009

Proteomic and Genetic Approaches Identify Syk as an AML Target

Por Hahn, Cynthia K., Berchuck, Jacob E., Ross, Kenneth N., Kakoza, Rose M., Clauser, Karl, Schinzel, Anna C., Ross, Linda, Galinsky, Ilene, Davis, Tina N., Silver, Serena J., Root, David E., Stone, Richard M., DeAngelo, Daniel J., Carroll, Martin, Hahn, William C., Carr, Steven A., Golub, Todd R., Kung, Andrew L., Stegmaier, Kimberly
Publicado em 2009

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

Por Firestein, Ron, Bass, Adam J., Kim, So Young, Dunn, Ian F., Silver, Serena J., Guney, Isil, Freed, Ellen, Ligon, Azra H., Vena, Natalie, Ogino, Shuji, Chheda, Milan G., Tamayo, Pablo, Finn, Stephen, Shrestha, Yashaswi, Boehm, Jesse S., Jain, Supriya, Bojarski, Emeric, Mermel, Craig, Barretina, Jordi, Chan, Jennifer A., Baselga, Jose, Tabernero, Josep, Root, David E., Fuchs, Charles S., Loda, Massimo, Shivdasani, Ramesh A., Meyerson, Matthew, Hahn, William C.
Publicado em 2008

An epigenetic mechanism of resistance to targeted therapy in T-cell acute lymphoblastic leukemia

Por Knoechel, Birgit, Roderick, Justine E., Williamson, Kaylyn E., Zhu, Jiang, Lohr, Jens G., Cotton, Matthew J., Gillespie, Shawn M., Fernandez, Daniel, Ku, Manching, Wang, Hongfang, Piccioni, Federica, Silver, Serena J., Jain, Mohit, Pearson, Daniel, Kluk, Michael J., Ott, Christopher J., Shultz, Leonard D., Brehm, Michael A., Greiner, Dale L., Gutierrez, Alejandro, Stegmaier, Kimberly, Kung, Andrew L., Root, David E., Bradner, James E., Aster, Jon C., Kelliher, Michelle A., Bernstein, Bradley E.
Publicado em 2014

The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(–) stem cell–like breast cancer cells in human tumors

Por Marotta, Lauren L.C., Almendro, Vanessa, Marusyk, Andriy, Shipitsin, Michail, Schemme, Janina, Walker, Sarah R., Bloushtain-Qimron, Noga, Kim, Jessica J., Choudhury, Sibgat A., Maruyama, Reo, Wu, Zhenhua, Gönen, Mithat, Mulvey, Laura A., Bessarabova, Marina O., Huh, Sung Jin, Silver, Serena J., Kim, So Young, Park, So Yeon, Lee, Hee Eun, Anderson, Karen S., Richardson, Andrea L., Nikolskaya, Tatiana, Nikolsky, Yuri, Liu, X. Shirley, Root, David E., Hahn, William C., Frank, David A., Polyak, Kornelia
Publicado em 2011

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state

Por Chudnovsky, Yakov, Kim, Dohoon, Zheng, Siyuan, Whyte, Warren A., Bansal, Mukesh, Bray, Mark-Anthony, Gopal, Shuba, Theisen, Matthew A., Bilodeau, Steve, Thiru, Prathapan, Muffat, Julien, Yilmaz, Omer H., Mitalipova, Maya, Woolard, Kevin, Lee, Jeongwu, Nishimura, Riko, Sakata, Nobuo, Fine, Howard A., Carpenter, Anne E., Silver, Serena J., Verhaak, Roel G. W., Califano, Andrea, Young, Richard A., Ligon, Keith L., Mellinghoff, Ingo K., Root, David E., Sabatini, David M., Hahn, William C., Chheda, Milan G.
Publicado em 2014

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

Por Barbie, David A., Tamayo, Pablo, Boehm, Jesse S., Kim, So Young, Moody, Susan E., Dunn, Ian F., Schinzel, Anna C., Sandy, Peter, Meylan, Etienne, Scholl, Claudia, Fröhling, Stefan, Chan, Edmond M., Sos, Martin L., Michel, Kathrin, Mermel, Craig, Silver, Serena J., Weir, Barbara A., Reiling, Jan H., Sheng, Qing, Gupta, Piyush B., Wadlow, Raymond C., Le, Hanh, Hoersch, Sebastian, Wittner, Ben S., Ramaswamy, Sridhar, Livingston, David M., Sabatini, David M., Meyerson, Matthew, Thomas, Roman K., Lander, Eric S., Mesirov, Jill P., Root, David E., Gilliland, D. Gary, Jacks, Tyler, Hahn, William C.
Publicado em 2009

Integrative screening approach identifies regulators of polyploidization and targets for acute megakaryocytic leukemia

Por Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vladimir, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy, An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James, Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.
Publicado em 2012