Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a)

Por Guney, Isil, Wu, Shirley, Sedivy, John M.
Publicado em 2006

Integrative genomic approaches to understanding cancer

Por Hahn, William C., Dunn, Ian F., Kim, So Young, Schinzel, Anna C., Firestein, Ron, Guney, Isil, Boehm, Jesse S.
Publicado em 2009

Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation

Por Tamura, Kiyoshi, Hua, Bayin, Adachi, Susumu, Guney, Isil, Kawauchi, Junya, Morioka, Masaki, Tamamori-Adachi, Mimi, Tanaka, Yujiro, Nakabeppu, Yusaku, Sunamori, Makoto, Sedivy, John M, Kitajima, Shigetaka
Publicado em 2005

BRAF Activation Initiates but Does Not Maintain Invasive Prostate Adenocarcinoma

Por Jeong, Joseph H., Wang, Zhenxiong, Guimaraes, Alexander S., Ouyang, Xuesong, Figueiredo, Jose L., Ding, Zhihu, Jiang, Shan, Guney, Isil, Kang, Gyeong Hoon, Shin, Eyoung, Hahn, William C., Loda, Massimo F., Abate-Shen, Cory, Weissleder, Ralph, Chin, Lynda
Publicado em 2008

An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-κB

Por Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K., Reczek, Elizabeth E., De Raedt, Thomas, Guney, Isil, Strochlic, David E., Laura, E., Beroukhim, Rameen, Bronson, Roderick T., Ryeom, Sandra, Hahn, William C., Loda, Massimo, Cichowski, Karen
Publicado em 2010

Castration resistance in prostate cancer is mediated by the kinase NEK6

Por Choudhury, Atish D., Schinzel, Anna C., Cotter, Maura B., Lis, Rosina T., Labella, Katherine, Lock, Ying Jie, Izzo, Francesca, Guney, Isil, Bowden, Michaela, Li, Yvonne Y., Patel, Jinal, Hartman, Emily, Carr, Steven A., Schenone, Monica, Jaffe, Jacob D., Kantoff, Philip W., Hammerman, Peter S., Hahn, William C.
Publicado no Cancer Res (2016)

A prostatic intraepithelial neoplasia-dependent p27(kip1) checkpoint induces senescence, inhibits cell proliferation and cancer progression

Por Majumder, Pradip K., Grisanzio, Chiara, O’Connell, Fionnuala, Barry, Marc, Brito, Joseph M., Xu, Qing, Guney, Isil, Berger, Raanan, Herman, Paula, Bikoff, Rachel, Fedele, Giuseppe, Baek, Won-Ki, Wang, Shunyou, Ellwood-Yen, Katharine, Wu, Hong, Sawyers, Charles L., Signoretti, Sabina, Hahn, William C., Loda, Massimo, Sellers, William R.
Publicado em 2008

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

Por Firestein, Ron, Bass, Adam J., Kim, So Young, Dunn, Ian F., Silver, Serena J., Guney, Isil, Freed, Ellen, Ligon, Azra H., Vena, Natalie, Ogino, Shuji, Chheda, Milan G., Tamayo, Pablo, Finn, Stephen, Shrestha, Yashaswi, Boehm, Jesse S., Jain, Supriya, Bojarski, Emeric, Mermel, Craig, Barretina, Jordi, Chan, Jennifer A., Baselga, Jose, Tabernero, Josep, Root, David E., Fuchs, Charles S., Loda, Massimo, Shivdasani, Ramesh A., Meyerson, Matthew, Hahn, William C.
Publicado em 2008