The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy

od Liu, Suhu, Marneth, Anna E., Alexe, Gabriela, Walker, Sarah R., Gandler, Helen I., Ye, Darwin Q., Labella, Katherine, Mathur, Radhika, Toniolo, Patricia A., Tillgren, Michelle, Gokhale, Prafulla C., Barbie, David, Mullally, Ann, Stegmaier, Kimberly, Frank, David A.
Wydane w Blood Adv (2018)

Castration resistance in prostate cancer is mediated by the kinase NEK6

od Choudhury, Atish D., Schinzel, Anna C., Cotter, Maura B., Lis, Rosina T., Labella, Katherine, Lock, Ying Jie, Izzo, Francesca, Guney, Isil, Bowden, Michaela, Li, Yvonne Y., Patel, Jinal, Hartman, Emily, Carr, Steven A., Schenone, Monica, Jaffe, Jacob D., Kantoff, Philip W., Hammerman, Peter S., Hahn, William C.
Wydane w Cancer Res (2016)

Development of Selective Covalent Janus Kinase 3 Inhibitors

od Tan, Li, Akahane, Koshi, McNally, Randall, Reyskens, Kathleen M. S. E., Ficarro, Scott B., Liu, Suhu, Herter-Sprie, Grit S., Koyama, Shohei, Pattison, Michael J., Labella, Katherine, Johannessen, Liv, Akbay, Esra A., Wong, Kwok-Kin, Frank, David A., Marto, Jarrod A., Look, Thomas A., Arthur, J. Simon C., Eck, Michael J., Gray, Nathanael S.
Wydane w J Med Chem (2015)

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer

od Li, Ji, Choi, Peter S, Chaffer, Christine L, Labella, Katherine, Hwang, Justin H, Giacomelli, Andrew O, Kim, Jong Wook, Ilic, Nina, Doench, John G, Ly, Seav Huong, Dai, Chao, Hagel, Kimberly, Hong, Andrew L, Gjoerup, Ole, Goel, Shom, Ge, Jennifer Y, Root, David E, Zhao, Jean J, Brooks, Angela N, Weinberg, Robert A, Hahn, William C
Wydane w eLife (2018)

Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition

od Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles WM, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C
Wydane w eLife (2019)