(18)FDG-PET predicts pharmacodynamic response to OSI-906, a dual IGF-1R/IR inhibitor, in preclinical mouse models of lung cancer

le McKinley, Eliot T., Bugaj, Joseph E., Zhao, Ping, Guleryuz, Saffet, Mantis, Christine, Gokhale, Prafulla C., Wild, Robert, Manning, H. Charles
Foilsithe 2011

Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors

le Falcon, Beverly L., Barr, Sharon, Gokhale, Prafulla C., Chou, Jeyling, Fogarty, Jennifer, Depeille, Philippe, Miglarese, Mark, Epstein, David M., McDonald, Donald M.
Foilsithe 2011

IMMU-19. PD-1 BLOCKADE ACTIVATES CD4 T CELLS AND THE INNATE IMMUNE RESPONSE FOR GLIOBLASTOMA ERADICATION

le Speranza, Maria Carmela, Klein, Sarah R, Gokhale, Prafulla C, Wilkens, Margaret K, Jones, Kristen L, Chaudhri, Apoorvi, Kirschmeier, Paul T, Reardon, David, Freeman, Gordon
Foilsithe in Neuro Oncol (2018)

IMMU-15. PD-1 BLOCKADE ACTIVATES CD4 T CELLS AND THE INNATE IMMUNE RESPONSE FOR GLIOBLASTOMA ERADICATION

le Klein, Sarah R, Speranza, Maria Carmela, Gokhale, Prafulla C, Wilkens, Margaret K, Jones, Kristen L, Kirschmeier, Paul T, Chaudhri, Apoorvi, Reardon, David, Freeman, Gordon J
Foilsithe in Neuro Oncol (2017)

Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells

le Patacsil, Dorrelyn, Osayi, Sylvester, Tran, Anh Thu, Saenz, Francisco, Yimer, Lydia, Shajahan, Ayesha N., Gokhale, Prafulla C., Verma, Mukesh, Clarke, Robert, Chauhan, Subhash C., Kumar, Deepak
Foilsithe 2011

Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response

le Park, Donglim Esther, Cheng, Jingwei, Berrios, Christian, Montero, Joan, Cortés-Cros, Marta, Ferretti, Stéphane, Arora, Reety, Tillgren, Michelle L., Gokhale, Prafulla C., DeCaprio, James A.
Foilsithe in Proc Natl Acad Sci U S A (2019)

Acute pharmacological degradation of Helios destabilizes regulatory T cells

le Wang, Eric S., Verano, Alyssa L., Nowak, Radosław P., Yuan, J. Christine, Donovan, Katherine A., Eleuteri, Nicholas A., Yue, Hong, Ngo, Kenneth H., Lizotte, Patrick H., Gokhale, Prafulla C., Gray, Nathanael S., Fischer, Eric S.
Foilsithe in Nat Chem Biol (2021)

Effects of the multi‐kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia

le Weisberg, Ellen, Meng, Chengcheng, Case, Abigail E., Tiv, Hong L., Gokhale, Prafulla C., Buhrlage, Sara J., Yang, Jing, Liu, Xiaoxi, Wang, Jinhua, Gray, Nathanael, Adamia, Sophia, Sattler, Martin, Stone, Richard, Griffin, James D.
Foilsithe in J Cell Mol Med (2020)

LRRC15 Targeting in Soft-Tissue Sarcomas: Biological and Clinical Implications

le Ben-Ami, Eytan, Perret, Raul, Huang, Ying, Courgeon, Félicie, Gokhale, Prafulla C., Laroche-Clary, Audrey, Eschle, Benjamin K., Velasco, Valérie, Le Loarer, François, Algeo, Marie-Paule, Purcell, James, Demetri, George D., Italiano, Antoine
Foilsithe in Cancers (Basel) (2020)

The combination of FLT3 and SYK kinase inhibitors is toxic to leukaemia cells with CBL mutations

le Weisberg, Ellen, Meng, Chengcheng, Case, Abigail E., Tiv, Hong L., Gokhale, Prafulla C., Toure, Anthia A., Buhrlage, Sara, Liu, Xiaoxi, Wang, Jinhua, Gray, Nathanael, Stone, Richard, Adamia, Sophia, Winer, Eric, Sattler, Martin, Griffin, James D.
Foilsithe in J Cell Mol Med (2020)

Evaluation of ERK as a therapeutic target in acute myelogenous leukemia A novel ERK inhibitor for AML

le Weisberg, Ellen, Meng, Chengcheng, Case, Abigail, Sattler, Martin, Tiv, Hong L., Gokhale, Prafulla C., Buhrlage, Sara, Wang, Jinhua, Gray, Nathanael, Stone, Richard, Liu, Suiyang, Bhagwat, Shripad V., Tiu, Ramon V., Adamia, Sophia, Griffin, James D.
Foilsithe in Leukemia (2019)

Comparison of effects of midostaurin, crenolanib, quizartinib, gilteritinib, sorafenib and BLU-285 on oncogenic mutants of KIT and FLT3 in hematologic malignancies: Mutant KIT and...

le Weisberg, Ellen, Meng, Chengcheng, Case, Abigail, Sattler, Martin, Tiv, Hong L., Gokhale, Prafulla C., Buhrlage, Sara, Liu, Xiaoxi, Yang, Jing, Wang, Jinhua, Gray, Nathanael, Stone, Richard, Adamia, Sophia, Dubreuil, Patrice, Letard, Sebastien, Griffin, James D.
Foilsithe in Br J Haematol (2019)

Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C

le Kedves, Alexia T., Gleim, Scott, Liang, Xiaoyou, Bonal, Dennis M., Sigoillot, Frederic, Harbinski, Fred, Sanghavi, Sneha, Benander, Christina, George, Elizabeth, Gokhale, Prafulla C., Nguyen, Quang-De, Kirschmeier, Paul T., Distel, Robert J., Jenkins, Jeremy, Goldberg, Michael S., Forrester, William C.
Foilsithe in J Clin Invest (2017)

The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy

le Liu, Suhu, Marneth, Anna E., Alexe, Gabriela, Walker, Sarah R., Gandler, Helen I., Ye, Darwin Q., Labella, Katherine, Mathur, Radhika, Toniolo, Patricia A., Tillgren, Michelle, Gokhale, Prafulla C., Barbie, David, Mullally, Ann, Stegmaier, Kimberly, Frank, David A.
Foilsithe in Blood Adv (2018)

Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis

le Park, Donglim Esther, Cheng, Jingwei, McGrath, John P., Lim, Matthew Y., Cushman, Camille, Swanson, Selene K., Tillgren, Michelle L., Paulo, Joao A., Gokhale, Prafulla C., Florens, Laurence, Washburn, Michael P., Trojer, Patrick, DeCaprio, James A.
Foilsithe in Nat Cell Biol (2020)

Author Correction: Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis

le Park, Donglim Esther, Cheng, Jingwei, McGrath, John P., Lim, Matthew Y., Cushman, Camille, Swanson, Selene K., Tillgren, Michelle L., Paulo, Joao A., Gokhale, Prafulla C., Florens, Laurence, Washburn, Michael P., Trojer, Patrick, DeCaprio, James A.
Foilsithe in Nat Cell Biol (2020)

Discovery of Novel Insulin-Like Growth Factor-1 Receptor Inhibitors with Unique Time-Dependent Binding Kinetics

le Jin, Meizhong, Petronella, Brenda A., Cooke, Andy, Kadalbajoo, Mridula, Siu, Kam W., Kleinberg, Andrew, May, Earl W., Gokhale, Prafulla C., Schulz, Ryan, Kahler, Jennifer, Bittner, Mark A., Foreman, Kenneth, Pachter, Jonathan A., Wild, Robert, Epstein, David, Mulvihill, Mark J.
Foilsithe 2013

Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations

le Ogino, Atsuko, Choi, Jihyun, Lin, Mika, Wilkens, Margaret K., Calles, Antonio, Xu, Man, Adeni, Anika E., Chambers, Emily S., Capelletti, Marzia, Butaney, Mohit, Gray, Nathanael S., Gokhale, Prafulla C., Palakurthi, Sangeetha, Kirschmeier, Paul, Oxnard, Geoffrey R., Sholl, Lynette M., Jänne, Pasi A.
Foilsithe in Mol Oncol (2020)

Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs

le Flavahan, William A, Drier, Yotam, Johnstone, Sarah E., Hemming, Matthew L., Tarjan, Daniel R., Hegazi, Esmat, Shareef, Sarah J., Javed, Nauman M., Raut, Chandrajit P., Eschle, Benjamin K., Gokhale, Prafulla C., Hornick, Jason L., Sicinska, Ewa T., Demetri, George D., Bernstein, Bradley E.
Foilsithe in Nature (2019)

Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM)

le Lapidot, Moshe, Case, Abigail E., Larios, Dalia, Gandler, Helen I., Meng, Chengcheng, Tošić, Isidora, Weisberg, Ellen L., Poitras, Michael J., Gokhale, Prafulla C., Paweletz, Cloud P., Podar, Klaus, Salgia, Ravi, Saladi, Srinivas V., Griffin, James D., Frank, David A., Bueno, Raphael, Sattler, Martin
Foilsithe in Cancers (Basel) (2020)