Structural reengineering of imatinib to decrease cardiac risk in cancer therapy

Por Demetri, George D.
Publicado em 2007

Why tyrosine kinase inhibitor resistance is common in advanced gastrointestinal stromal tumors

Por Tomasetti, Cristian, Demetri, George D, Parmigiani, Giovanni
Publicado em 2013

Whole Lung Irradiation in Adults with Metastatic Ewing Sarcoma: Practice Patterns and Implications for Treatment

Por Tanguturi, Shyam K., George, Suzanne, Marcus, Karen J., Demetri, George D., Baldini, Elizabeth H.
Publicado no Sarcoma (2015)

Protein Kinase C Theta (PKCθ) Regulates KIT Expression and Proliferation in Gastrointestinal Stromal Tumors

Por Ou, Wen-bin, Zhu, Mei-jun, Demetri, George D., Fletcher, Christopher DM, Fletcher, Jonathan A.
Publicado em 2008

Optimizing Treatment Outcomes With Regorafenib: Personalized Dosing and Other Strategies to Support Patient Care

Por Grothey, Axel, George, Suzanne, van Cutsem, Eric, Blay, Jean-Yves, Sobrero, Alberto, Demetri, George D.
Publicado em 2014

Adults With Ewing’s Sarcoma/Primitive Neuroectodermal Tumor: Adverse Effect of Older Age and Primary Extraosseous Disease on Outcome

Por Baldini, Elizabeth H., Demetri, George D., Fletcher, Christopher D. M., Foran, James, Marcus, Karen C., Singer, Samuel
Publicado em 1999

STRONG EXPRESSION OF IGF1R IN PEDIATRIC GASTROINTESTINAL STROMAL TUMORS WITHOUT IGF1R GENOMIC AMPLIFICATION

Por Janeway, Katherine A., Zhu, Mei-Jun, Barretina, Jordi, Perez-Atayde, Antonio, Demetri, George D., Fletcher, Jonathan A.
Publicado em 2010

Regorafenib for advanced gastrointestinal stromal tumors following imatinib and sunitinib treatment: a subgroup analysis evaluating Japanese patients in the phase III GRID trial

Por Komatsu, Yoshito, Doi, Toshihiko, Sawaki, Akira, Kanda, Tatsuo, Yamada, Yasuhide, Kuss, Iris, Demetri, George D, Nishida, Toshirou
Publicado no Int J Clin Oncol (2015)

Cardio-Oncology: How New Targeted Cancer Therapies and Precision Medicine Can Inform Cardiovascular Discovery

Por Bellinger, Andrew M., Arteaga, Carlos L., Force, Thomas, Humphreys, Benjamin D., Demetri, George D., Druker, Brian J., Moslehi, Javid
Publicado no Circulation (2015)

Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma

Por Demetri, George D., Fletcher, Christopher D. M., Mueller, Elisabetta, Sarraf, Pasha, Naujoks, Ryan, Campbell, Natalee, Spiegelman, Bruce M., Singer, Samuel
Publicado em 1999

Response to Chemotherapy and Predictors of Survival in Adult Rhabdomyosarcoma

Por Esnaola, Nestor F., Rubin, Brian P., Baldini, Elizabeth H., Vasudevan, Naren, Demetri, George D., Fletcher, Christopher D. M., Singer, Samuel
Publicado em 2001

Effect of gastrointestinal resection on sunitinib exposure in patients with GIST

Por de Wit, Djoeke, van Erp, Nielka P, Khosravan, Reza, Wiltshire, Robin, Allred, Randy, Demetri, George D, Guchelaar, Henk-Jan, Gelderblom, Hans
Publicado em 2014

Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma

Por Nakayama, Robert, Zhang, Yi-Xiang, Czaplinski, Jeffrey T., Anatone, Alex J., Sicinska, Ewa T., Fletcher, Jonathan A., Demetri, George D., Wagner, Andrew J.
Publicado no Oncotarget (2016)

Comparison of Performance of Various Tumor Response Criteria in Assessment of Regorafenib Activity in Advanced Gastrointestinal Stromal Tumors after Failure of Imatinib and Sunitin...

Por Shinagare, Atul B., Jagannathan, Jyothi P., Kurra, Vikram, Urban, Trinity, Manola, Judith, Choy, Edwin, Demetri, George D., George, Suzanne, Ramaiya, Nikhil H.
Publicado no Eur J Cancer (2014)

A phase 1 study of the heat shock protein 90 inhibitor retaspimycin hydrochloride (IPI-504) in patients with gastrointestinal stromal tumors or soft tissue sarcomas

Por Wagner, Andrew J., Chugh, Rashmi, Rosen, Lee S., Morgan, Jeffrey A., George, Suzanne, Gordon, Michael, Dunbar, Joi, Normant, Emmanuel, Grayzel, David, Demetri, George D.
Publicado no Clin Cancer Res (2013)

A retrospective chart review of drug treatment patterns and clinical outcomes among patients with metastatic or recurrent soft tissue sarcoma refractory to one or more prior chemot...

Por Wagner, Michael J, Amodu, Leo Ismaila, Duh, Mei Sheng, Korves, Caroline, Solleza, Franco, Manson, Stephanie C, Diaz, José, Neary, Maureen P, Demetri, George D
Publicado no BMC Cancer (2015)

Effects of Sorafenib on Intra-Tumoral Interstitial Fluid Pressure and Circulating Biomarkers in Patients with Refractory Sarcomas (NCI Protocol 6948)

Por Raut, Chandrajit P., Boucher, Yves, Duda, Dan G., Morgan, Jeffrey A., Quek, Richard, Ancukiewicz, Marek, Lahdenranta, Johanna, Eder, J. Paul, Demetri, George D., Jain, Rakesh K.
Publicado em 2012

Key Issues in the Clinical Management of Gastrointestinal Stromal Tumors: An Expert Discussion

Por Maki, Robert G., Blay, Jean-Yves, Demetri, George D., Fletcher, Jonathan A., Joensuu, Heikki, Martín-Broto, Javier, Nishida, Toshirou, Reichardt, Peter, Schöffski, Patrick, Trent, Jonathan C.
Publicado no Oncologist (2015)

c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas

Por Sioletic, Stefano, Czaplinski, Jeffrey, Hu, Lan, Fletcher, Jonathan A., Fletcher, Christopher D.M., Wagner, Andrew J., Loda, Massimo, Demetri, George D., Sicinska, Ewa T., Snyder, Eric L.
Publicado no J Pathol (2014)

Phase II Trial of Neoadjuvant/Adjuvant Imatinib Mesylate (IM) for Advanced Primary and Metastatic/Recurrent Operable Gastrointestinal Stromal Tumor (GIST) – early results of RTOG 0...

Por Eisenberg, Burton L., Harris, Jonathan, Blanke, Charles, Demetri, George D., Heinrich, Michael C., Watson, James C., Hoffman, John P., Okuno, Scott, Kane, John M., von Mehren, Margaret
Publicado em 2009