Optimizing Treatment Outcomes With Regorafenib: Personalized Dosing and Other Strategies to Support Patient Care

Regorafenib is an oral multikinase inhibitor that inhibits several kinases relevant to tumor biology in several cancers, including colorectal carcinoma (CRC) and gastrointestinal stromal tumor (GIST). In phase III trials, regorafenib significantly improved overall survival versus placebo in patients...

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Bibliografiske detaljer
Main Authors: Grothey, Axel, George, Suzanne, van Cutsem, Eric, Blay, Jean-Yves, Sobrero, Alberto, Demetri, George D.
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2014
Fag:
Symptom Management and Supportive Care
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041675/
https://ncbi.nlm.nih.gov/pubmed/24821824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0059
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