Preemptive Versus Reactive Topical Clobetasol for Regorafenib‐Induced Hand‐Foot Reactions: A Preplanned Analysis of the ReDOS Trial

BACKGROUND: Hand‐foot skin reaction (HFSR) is the most common regorafenib‐induced adverse event and is in need of effective prevention and palliation. MATERIALS AND METHODS: The Regorafenib Dose Optimization Study (ReDOS), a four‐arm, previously published trial with a 1:1:1:1 randomization scheme, w...

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Veröffentlicht in:Oncologist
Hauptverfasser: Jatoi, Aminah, Ou, Fang‐Shu, Ahn, Daniel H., Zemla, Tyler J., Le‐Rademacher, Jennifer G., Boland, Patrick, Ciombor, Kristen K., Jacobs, Nisha L., Pasche, Boris, Cleary, James M., McCune, Jeannine S., Pedersen, Katrina S., Barzi, Afsaneh, Chiorean, E. Gabriela, Heying, Erica N., Lenz, Heinz‐Josef, Sloan, Jeff A., Grothey, Axel, Lacouture, Mario E., Bekaii‐Saab, Tanios
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2021
Schlagworte:
Symptom Management and Supportive Care
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265366/
https://ncbi.nlm.nih.gov/pubmed/33604969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/onco.13730
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