Preemptive Versus Reactive Topical Clobetasol for Regorafenib‐Induced Hand‐Foot Reactions: A Preplanned Analysis of the ReDOS Trial

BACKGROUND: Hand‐foot skin reaction (HFSR) is the most common regorafenib‐induced adverse event and is in need of effective prevention and palliation. MATERIALS AND METHODS: The Regorafenib Dose Optimization Study (ReDOS), a four‐arm, previously published trial with a 1:1:1:1 randomization scheme, w...

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Pubblicato in:Oncologist
Autori principali: Jatoi, Aminah, Ou, Fang‐Shu, Ahn, Daniel H., Zemla, Tyler J., Le‐Rademacher, Jennifer G., Boland, Patrick, Ciombor, Kristen K., Jacobs, Nisha L., Pasche, Boris, Cleary, James M., McCune, Jeannine S., Pedersen, Katrina S., Barzi, Afsaneh, Chiorean, E. Gabriela, Heying, Erica N., Lenz, Heinz‐Josef, Sloan, Jeff A., Grothey, Axel, Lacouture, Mario E., Bekaii‐Saab, Tanios
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2021
Soggetti:
Symptom Management and Supportive Care
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265366/
https://ncbi.nlm.nih.gov/pubmed/33604969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/onco.13730
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