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Optimizing Treatment Outcomes With Regorafenib: Personalized Dosing and Other Strategies to Support Patient Care

Regorafenib is an oral multikinase inhibitor that inhibits several kinases relevant to tumor biology in several cancers, including colorectal carcinoma (CRC) and gastrointestinal stromal tumor (GIST). In phase III trials, regorafenib significantly improved overall survival versus placebo in patients...

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Main Authors: Grothey, Axel, George, Suzanne, van Cutsem, Eric, Blay, Jean-Yves, Sobrero, Alberto, Demetri, George D.
格式: Artigo
語言:Inglês
出版: AlphaMed Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041675/
https://ncbi.nlm.nih.gov/pubmed/24821824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0059
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