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Effect of gastrointestinal resection on sunitinib exposure in patients with GIST
BACKGROUND: GIST patients often undergo GI-surgery. Previous studies have shown that imatinib and nilotinib exposures were decreased in GIST patients with prior major gastrectomy. We investigated whether major gastrectomy influences the exposure to sunitinib and its active metabolite SU12662. METHOD...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133599/ https://ncbi.nlm.nih.gov/pubmed/25102852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-575 |
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