Effect of gastrointestinal resection on sunitinib exposure in patients with GIST

BACKGROUND: GIST patients often undergo GI-surgery. Previous studies have shown that imatinib and nilotinib exposures were decreased in GIST patients with prior major gastrectomy. We investigated whether major gastrectomy influences the exposure to sunitinib and its active metabolite SU12662. METHOD...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: de Wit, Djoeke, van Erp, Nielka P, Khosravan, Reza, Wiltshire, Robin, Allred, Randy, Demetri, George D, Guchelaar, Henk-Jan, Gelderblom, Hans
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133599/
https://ncbi.nlm.nih.gov/pubmed/25102852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-575
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