Targeting PDGF Signaling in Carcinoma-Associated Fibroblasts Controls Cervical Cancer in Mouse Model

Por Jain, Rakesh K, Lahdenranta, Johanna, Fukumura, Dai
Publicado em 2008

SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast

Por Jäntti, Jussi, Lahdenranta, Johanna, Olkkonen, Vesa M., Söderlund, Hans, Keränen, Sirkka
Publicado em 1999

CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

Por Bhagwat, Shripad V., Lahdenranta, Johanna, Giordano, Ricardo J., Arap, Wadih, Pasqualini, Renata, Shapiro, Linda H.
Publicado no Blood (2001)

Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis

Por Lahdenranta, Johanna, Hagendoorn, Jeroen, Padera, Timothy P., Hoshida, Tohru, Nelson, Gregory, Kashiwagi, Satoshi, Jain, Rakesh K., Fukumura, Dai
Publicado em 2009

HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B

Por Kirouac, Daniel C., Du, Jinyan, Lahdenranta, Johanna, Onsum, Matthew D., Nielsen, Ulrik B., Schoeberl, Birgit, McDonagh, Charlotte F.
Publicado no PLoS Comput Biol (2016)

An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration

Por Lahdenranta, Johanna, Pasqualini, Renata, Schlingemann, Reinier O., Hagedorn, Martin, Stallcup, William B., Bucana, Corazon D., Sidman, Richard L., Arap, Wadih
Publicado em 2001

Development of a Ligand-Directed Approach To Study the Pathogenesis of Invasive Aspergillosis

Por Lionakis, Michail S., Lahdenranta, Johanna, Sun, Jessica, Liu, Wei, Lewis, Russell E., Albert, Nathaniel D., Pasqualini, Renata, Arap, Wadih, Kontoyiannis, Dimitrios P.
Publicado em 2005

Aminopeptidase N Is a Receptor for Tumor-homing Peptides and a Target for Inhibiting Angiogenesis

Por Pasqualini, Renata, Koivunen, Erkki, Kain, Renate, Lahdenranta, Johanna, Sakamoto, Michiie, Stryhn, Anette, Ashmun, Richard A., Shapiro, Linda H., Arap, Wadih, Ruoslahti, Erkki
Publicado no Cancer Res (2000)

Anti–Vascular Endothelial Growth Factor Therapies as a Novel Therapeutic Approach to Treating Neurofibromatosis-Related Tumors

Por Wong, Hon Kit, Lahdenranta, Johanna, Kamoun, Walid S., Chan, Annie W., McClatchey, Andrea I., Plotkin, Scott R., Jain, Rakesh K., di Tomaso, Emmanuelle
Publicado no Cancer Res (2010)

Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse

Por Giordano, Ricardo J., Lahdenranta, Johanna, Zhen, Lijie, Chukwueke, Ugonma, Petrache, Irina, Langley, Robert R., Fidler, Isaiah J., Pasqualini, Renata, Tuder, Rubin M., Arap, Wadih
Publicado em 2008

Effects of Sorafenib on Intra-Tumoral Interstitial Fluid Pressure and Circulating Biomarkers in Patients with Refractory Sarcomas (NCI Protocol 6948)

Por Raut, Chandrajit P., Boucher, Yves, Duda, Dan G., Morgan, Jeffrey A., Quek, Richard, Ancukiewicz, Marek, Lahdenranta, Johanna, Eder, J. Paul, Demetri, George D., Jain, Rakesh K.
Publicado em 2012

A “Vascular Normalization Index” as Potential Mechanistic Biomarker to Predict Survival after a Single Dose of Cediranib in Recurrent Glioblastoma Patients

Por Sorensen, A. Gregory, Batchelor, Tracy T., Zhang, Wei-Ting, Chen, Poe-Jou, Yeo, Priscilla, Wang, Meiyun, Jennings, Dominique, Wen, Patrick Y., Lahdenranta, Johanna, Ancukiewicz, Marek, di Tomaso, Emmanuelle, Duda, Dan G., Jain, Rakesh K.
Publicado em 2009

Edema Control by Cediranib, a Vascular Endothelial Growth Factor Receptor–Targeted Kinase Inhibitor, Prolongs Survival Despite Persistent Brain Tumor Growth in Mice

Por Kamoun, Walid S., Ley, Carsten D., Farrar, Christian T., Duyverman, Annique M., Lahdenranta, Johanna, Lacorre, Delphine A., Batchelor, Tracy T., di Tomaso, Emmanuelle, Duda, Dan G., Munn, Lance L., Fukumura, Dai, Sorensen, A. Gregory, Jain, Rakesh K.
Publicado em 2009

A Ligand Peptide Motif Selected from a Cancer Patient Is a Receptor-Interacting Site within Human Interleukin-11

Por Cardó-Vila, Marina, Zurita, Amado J., Giordano, Ricardo J., Sun, Jessica, Rangel, Roberto, Guzman-Rojas, Liliana, Anobom, Cristiane D., Valente, Ana P., Almeida, Fábio C. L., Lahdenranta, Johanna, Kolonin, Mikhail G., Arap, Wadih, Pasqualini, Renata
Publicado em 2008

Efficacy, Safety, and Biomarkers of Neoadjuvant Bevacizumab, Radiation Therapy, and Fluorouracil in Rectal Cancer: A Multidisciplinary Phase II Study

Por Willett, Christopher G., Duda, Dan G., di Tomaso, Emmanuelle, Boucher, Yves, Ancukiewicz, Marek, Sahani, Dushyant V., Lahdenranta, Johanna, Chung, Daniel C., Fischman, Alan J., Lauwers, Gregory Y., Shellito, Paul, Czito, Brian G., Wong, Terence Z., Paulson, Erik, Poleski, Martin, Vujaskovic, Zeljko, Bentley, Rex, Chen, Helen X., Clark, Jeffrey W., Jain, Rakesh K.
Publicado em 2009

Efficacy, Safety, and Potential Biomarkers of Sunitinib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study

Por Zhu, Andrew X., Sahani, Dushyant V., Duda, Dan G., di Tomaso, Emmanuelle, Ancukiewicz, Marek, Catalano, Onofrio A., Sindhwani, Vivek, Blaszkowsky, Lawrence S., Yoon, Sam S., Lahdenranta, Johanna, Bhargava, Pankaj, Meyerhardt, Jeffrey, Clark, Jeffrey W., Kwak, Eunice L., Hezel, Aram F., Miksad, Rebecca, Abrams, Thomas A., Enzinger, Peter C., Fuchs, Charles S., Ryan, David P., Jain, Rakesh K.
Publicado em 2009