SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast

The exocyst is an essential multiprotein complex mediating polarized secretion in yeast. Here we describe a gene, SEM1, that can multicopy-suppress exocyst mutants sec3–2, sec8–9, sec10–2, and sec15–1. SEM1 is highly conserved among eukaryotic species. Its human homologue, DSS1, has been suggested a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Jäntti, Jussi, Lahdenranta, Johanna, Olkkonen, Vesa M., Söderlund, Hans, Keränen, Sirkka
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.909
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