A “Vascular Normalization Index” as Potential Mechanistic Biomarker to Predict Survival after a Single Dose of Cediranib in Recurrent Glioblastoma Patients

Early imaging or blood biomarkers of tumor response are desperately needed to customize antiangiogenic therapy for cancer patients. Anti–vascular endothelial growth factor (VEGF) therapy can “normalize” brain tumor vasculature by decreasing vessel diameter and permeability, and thinning the abnormal...

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Hlavní autoři: Sorensen, A. Gregory, Batchelor, Tracy T., Zhang, Wei-Ting, Chen, Poe-Jou, Yeo, Priscilla, Wang, Meiyun, Jennings, Dominique, Wen, Patrick Y., Lahdenranta, Johanna, Ancukiewicz, Marek, di Tomaso, Emmanuelle, Duda, Dan G., Jain, Rakesh K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824172/
https://ncbi.nlm.nih.gov/pubmed/19549889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-0814
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