Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse

Pulmonary gas exchange relies on a rich capillary network, which, together with alveolar epithelial type I and II cells, form alveolar septa, the functional units in the lung. Alveolar capillary endothelial cells are critical in maintaining alveolar structure, because disruption of endothelial cell...

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Main Authors: Giordano, Ricardo J., Lahdenranta, Johanna, Zhen, Lijie, Chukwueke, Ugonma, Petrache, Irina, Langley, Robert R., Fidler, Isaiah J., Pasqualini, Renata, Tuder, Rubin M., Arap, Wadih
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Metabolism and Bioenergetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570855/
https://ncbi.nlm.nih.gov/pubmed/18718906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804595200
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