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Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary Perspective

Emphysema consists of a unique pattern of alveolar destruction, resulting in marked airspace enlargement with reduction of alveolar capillary exchange area. Classical concepts of the pathogenesis of emphysema have relied on the paradigm set by the inflammation and protease/antiprotease imbalance. We...

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Detalhes bibliográficos
Main Authors: Tuder, Rubin M., Yoshida, Toshinori, Arap, Wadih, Pasqualini, Renata, Petrache, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647641/
https://ncbi.nlm.nih.gov/pubmed/16921129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200603-054MS
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