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Cellular and Molecular Mechanisms of Alveolar Destruction in Emphysema: An Evolutionary Perspective

Emphysema consists of a unique pattern of alveolar destruction, resulting in marked airspace enlargement with reduction of alveolar capillary exchange area. Classical concepts of the pathogenesis of emphysema have relied on the paradigm set by the inflammation and protease/antiprotease imbalance. We...

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Autors principals: Tuder, Rubin M., Yoshida, Toshinori, Arap, Wadih, Pasqualini, Renata, Petrache, Irina
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647641/
https://ncbi.nlm.nih.gov/pubmed/16921129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200603-054MS
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