Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek

Por Freeman, Gordon J.
Publicado em 2008

The Microsatellite Instable (MSI) Subset of Colorectal Cancer is a particularly good candidate for checkpoint blockade immunotherapy

Por Xiao, Yanping, Freeman, Gordon J.
Publicado no Cancer Discov (2015)

A new B7:CD28 family checkpoint target for cancer immunotherapy: HHLA2

Por Xiao, Yanping, Freeman, Gordon J.
Publicado no Clin Cancer Res (2015)

A new therapeutic strategy for malaria: targeting T cell exhaustion

Por Freeman, Gordon J, Sharpe, Arlene H
Publicado em 2012

Costimulatory genes: Hotspots of conflict between host defense and autoimmunity

Por Jones, Jennifer C., Freeman, Gordon J.
Publicado em 2013

Therapeutic PD-1 Pathway Blockade Augments with other Modalities of Immunotherapy to Prevent Immune Decline in Ovarian Cancer

Por Duraiswamy, Jaikumar, Freeman, Gordon J., Coukos, George
Publicado em 2013

CD4(+)CD25(+) T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

Por Herman, Ann E., Freeman, Gordon J., Mathis, Diane, Benoist, Christophe
Publicado em 2004

Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T Cell Rejection Function in Tumors

Por Duraiswamy, Jaikumar, Kaluza, Karen M., Freeman, Gordon J., Coukos, George
Publicado em 2013

The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma

Por Mahoney, Kathleen M., Freeman, Gordon J., McDermott, David F.
Publicado no Clin Ther (2015)

The Leukocyte Semaphorin CD100 Is Expressed in Most T-Cell, but Few B-Cell, Non-Hodgkin’s Lymphomas

Por Dorfman, David M., Shahsafaei, Aliakbar, Nadler, Lee M., Freeman, Gordon J.
Publicado em 1998

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

Por Freeman, Gordon J., Wherry, E. John, Ahmed, Rafi, Sharpe, Arlene H.
Publicado em 2006

Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade

Por Blackburn, Shawn D., Shin, Haina, Freeman, Gordon J., Wherry, E. John
Publicado em 2008

The phosphatidylserine receptors, T cell immunoglobulin mucin proteins 3 and 4, are markers of histiocytic sarcoma and other histiocytic and dendritic cell neoplasms

Por Dorfman, David M., Hornick, Jason L., Shahsafaei, Aliakbar, Freeman, Gordon J.
Publicado em 2010

Programmed Death-1 (PD-1) is a Marker of Germinal Center-associated T Cells and Angioimmunoblastic T-Cell Lymphoma

Por Dorfman, David M., Brown, Julia A., Shahsafaei, Aliakbar, Freeman, Gordon J.
Publicado em 2006

Programmed Death-1 (PD-1):PD-Ligand 1 Interactions Inhibit TCR-Mediated Positive Selection of Thymocytes

Por Keir, Mary E., Latchman, Yvette E., Freeman, Gordon J., Sharpe, Arlene H.
Publicado em 2005

Role of PD-1 in regulating acute infections

Por Brown, Keturah E., Freeman, Gordon J., Wherry, E. John, Sharpe, Arlene H.
Publicado em 2010

TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

Por Freeman, Gordon J., Casasnovas, Jose M., Umetsu, Dale T., DeKruyff, Rosemarie H.
Publicado em 2010

Coinhibitory pathways in the B7-CD28 ligand-receptor family

Por Schildberg, Frank A., Klein, Sarah R., Freeman, Gordon J., Sharpe, Arlene H.
Publicado no Immunity (2016)

Molecular cloning of Porimin, a novel cell surface receptor mediating oncotic cell death

Por Ma, Fengrong, Zhang, Chonghui, Prasad, K. V. S., Freeman, Gordon J., Schlossman, Stuart F.
Publicado em 2001

Defective TFH cell function and increased TFR cells contribute to defective antibody production in aging

Por Sage, Peter T., Tan, Catherine L., Freeman, Gordon J., Haigis, Marcia, Sharpe, Arlene H.
Publicado no Cell Rep (2015)