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A new B7:CD28 family checkpoint target for cancer immunotherapy: HHLA2
HHLA2 is a newly identified B7 family member that modulates T cell functions through interaction with TMIGD2 and possibly a second receptor, with coinhibition in two studies and costimulation in one study. HHLA2 is expressed on a variety of human cancers, and its coinhibitory function makes it a can...
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| 出版年: | Clin Cancer Res |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433776/ https://ncbi.nlm.nih.gov/pubmed/25869386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2658 |
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