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The third group of the B7-CD28 immune checkpoint family: HHLA2, TMIGD2, B7x and B7-H3

The B7-CD28 family of ligands and receptors play important roles in T cell costimulation and coinhibition. Phylogenetically they can be divided into three groups. The recent discovery of the new molecules [B7-H3 (CD276), B7x (B7-H4/B7S1) and HHLA2 (B7H7/B7-H5)/TMIGD2 (IGPR-1/CD28H)] of the group III...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Janakiram, Murali, Shah, Urvi A, Liu, Weifeng, Zhao, Aimin, Schoenberg, Mark P, Zang, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338461/
https://ncbi.nlm.nih.gov/pubmed/28258693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12521
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