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HHLA2 and TMIGD2: new immunotherapeutic targets of the B7 and CD28 families

We and others recently discovered HHLA2 as a new B7 family member and transmembrane and immunoglobulin domain containing 2 (TMIGD2) as one of its receptors. Based on a new study we propose that HHLA2 may represent a novel immunosuppressive mechanism within the tumor microenvironment and hence could...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Janakiram, Murali, Chinai, Jordan M, Zhao, Aimin, Sparano, Joseph A, Zang, Xingxing
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570140/
https://ncbi.nlm.nih.gov/pubmed/26405587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1026534
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