IMMU-19. PD-1 BLOCKADE ACTIVATES CD4 T CELLS AND THE INNATE IMMUNE RESPONSE FOR GLIOBLASTOMA ERADICATION

Blockade of immune cell co-inhibitory receptor PD-1 using monoclonal antibodies (mAbs) allows the development of anti-tumor immunity in various solid tumors and lymphoid malignancies. We recently demonstrated that PD-1 blockade elicits an anti-tumor immune response resulting in tumor rejection and l...

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Publicado no:Neuro Oncol
Main Authors: Speranza, Maria Carmela, Klein, Sarah R, Gokhale, Prafulla C, Wilkens, Margaret K, Jones, Kristen L, Chaudhri, Apoorvi, Kirschmeier, Paul T, Reardon, David, Freeman, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217445/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.522
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