IMMU-10. EXPRESSION OF PD-L2, IN GLIOBLASTOMA; IMPLICATIONS AS A BIOMARKER FOR IMMUNOTHERAPY

Programmed cell death protein-1 (PD1) expressed on T cells is a key mediator of immune evasion via mediating the inhibition of T-cell function. This occurs via its binding to ligands PD-L1 and PD-L2 on tumor cells and other cells such as macrophages and microglia. Immune checkpoint blockade using an...

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Publicat a:Neuro Oncol
Autors principals: Ricklefs, Franz, Hayes, Josie, Speranza, Maria Carmela, Krenzlin, Harald, Costello, Joseph, Freeman, Gordon J, Westphal, Manfred, Lamszus, Katrin, Chiocca, E Antonio, Lawler, Sean E
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692796/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.469
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