Castration resistance in prostate cancer is mediated by the kinase NEK6

In prostate cancer, the development of castration resistance is pivotal in progression to aggressive disease. However, understanding of the pathways involved remains incomplete. In this study, we performed a high-throughput genetic screen to identify kinases that enable tumor formation by androgen-d...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Choudhury, Atish D., Schinzel, Anna C., Cotter, Maura B., Lis, Rosina T., Labella, Katherine, Lock, Ying Jie, Izzo, Francesca, Guney, Isil, Bowden, Michaela, Li, Yvonne Y., Patel, Jinal, Hartman, Emily, Carr, Steven A., Schenone, Monica, Jaffe, Jacob D., Kantoff, Philip W., Hammerman, Peter S., Hahn, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290202/
https://ncbi.nlm.nih.gov/pubmed/27899381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0455
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