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Castration resistance in prostate cancer is mediated by the kinase NEK6

In prostate cancer, the development of castration resistance is pivotal in progression to aggressive disease. However, understanding of the pathways involved remains incomplete. In this study, we performed a high-throughput genetic screen to identify kinases that enable tumor formation by androgen-d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Choudhury, Atish D., Schinzel, Anna C., Cotter, Maura B., Lis, Rosina T., Labella, Katherine, Lock, Ying Jie, Izzo, Francesca, Guney, Isil, Bowden, Michaela, Li, Yvonne Y., Patel, Jinal, Hartman, Emily, Carr, Steven A., Schenone, Monica, Jaffe, Jacob D., Kantoff, Philip W., Hammerman, Peter S., Hahn, William C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290202/
https://ncbi.nlm.nih.gov/pubmed/27899381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0455
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