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An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-κB

Metastasis is responsible for the majority of prostate cancer-related deaths; however, little is known about the molecular mechanisms that underlie this process. Here we identify an oncogene-tumor suppressor cascade that promotes prostate cancer initiation and metastasis by coordinately activating R...

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Detalhes bibliográficos
Main Authors: Min, Junxia, Zaslavsky, Alexander, Fedele, Giuseppe, McLaughlin, Sara K., Reczek, Elizabeth E., De Raedt, Thomas, Guney, Isil, Strochlic, David E., Laura, E., Beroukhim, Rameen, Bronson, Roderick T., Ryeom, Sandra, Hahn, William C., Loda, Massimo, Cichowski, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903662/
https://ncbi.nlm.nih.gov/pubmed/20154697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2100
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