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Genetic Interaction between Rb and K-ras in the Control of Differentiation and Tumor Suppression
Although the retinoblastoma protein (pRb) has been implicated in the processes of cellular differentiation, there is no compelling genetic or in vivo evidence that such activities contribute to pRb-mediated tumor suppression. Motivated by cell culture studies suggesting that Ras is a downstream effe...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529028/ https://ncbi.nlm.nih.gov/pubmed/15542848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10406-10415.2004 |
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