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Genetic Interaction between Rb and K-ras in the Control of Differentiation and Tumor Suppression

Although the retinoblastoma protein (pRb) has been implicated in the processes of cellular differentiation, there is no compelling genetic or in vivo evidence that such activities contribute to pRb-mediated tumor suppression. Motivated by cell culture studies suggesting that Ras is a downstream effe...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Takahashi, Chiaki, Contreras, Bernardo, Bronson, Roderick T., Loda, Massimo, Ewen, Mark E.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2004
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529028/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10406-10415.2004
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