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Genetic Interaction between Rb and K-ras in the Control of Differentiation and Tumor Suppression
Although the retinoblastoma protein (pRb) has been implicated in the processes of cellular differentiation, there is no compelling genetic or in vivo evidence that such activities contribute to pRb-mediated tumor suppression. Motivated by cell culture studies suggesting that Ras is a downstream effe...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529028/ https://ncbi.nlm.nih.gov/pubmed/15542848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10406-10415.2004 |
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