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The Retinoblastoma Protein Is Linked to the Activation of Ras

The inner membrane-bound protein Ras integrates various extracellular signals that are subsequently communicated from the cytoplasm to the nucleus via the Raf/MEK/MAPK cascade. Here we show that the retinoblastoma protein pRb, previously reported to be a nuclear target of this pathway, can in turn i...

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Detalhes bibliográficos
Main Authors: Lee, Kwang Youl, Ladha, Mohamed H., McMahon, Christine, Ewen, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84819/
https://ncbi.nlm.nih.gov/pubmed/10523661
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