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The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(–) stem cell–like breast cancer cells in human tumors
Intratumor heterogeneity is a major clinical problem because tumor cell subtypes display variable sensitivity to therapeutics and may play different roles in progression. We previously characterized 2 cell populations in human breast tumors with distinct properties: CD44(+)CD24(–) cells that have st...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3223826/ https://ncbi.nlm.nih.gov/pubmed/21633165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44745 |
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