CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

BACKGROUND: Aberrant β-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate β-catenin activity for therapeutic purposes have proven elusive to date. METHODOLOGY: To uncover genetic dependencies in breast cancer cells that...

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Bibliografiset tiedot
Päätekijät: Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2010
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813871/
https://ncbi.nlm.nih.gov/pubmed/20126544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008979
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