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CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

BACKGROUND: Aberrant β-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate β-catenin activity for therapeutic purposes have proven elusive to date. METHODOLOGY: To uncover genetic dependencies in breast cancer cells that...

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Main Authors: Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813871/
https://ncbi.nlm.nih.gov/pubmed/20126544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008979
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