CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

BACKGROUND: Aberrant β-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate β-catenin activity for therapeutic purposes have proven elusive to date. METHODOLOGY: To uncover genetic dependencies in breast cancer cells that...

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Bibliographic Details
Main Authors: Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813871/
https://ncbi.nlm.nih.gov/pubmed/20126544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008979
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