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ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor initiating cell state
Glioblastomas (GBM) harbor subpopulations of therapy-resistant tumor initiating cells (TICs) that are self-renewing and multipotent. To understand the regulation of the TIC state, we performed an image-based screen for genes regulating GBM TIC maintenance and identified ZFHX4, a 397-kDa transcriptio...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041390/ https://ncbi.nlm.nih.gov/pubmed/24440720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.032 |
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