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The tumour suppressor CHD5 forms a NuRD-type chromatin remodelling complex
Eukaryotic gene expression is developmentally regulated, in part by chromatin remodelling, and its dysregulation has been linked to cancer. CHD5 (chromodomain helicase DNA-binding protein 5) is a tumour suppressor gene (TSG) that maps to a region of consistent deletion on 1p36.31 in neuroblastomas (...
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| Publié dans: | Biochem J |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4487910/ https://ncbi.nlm.nih.gov/pubmed/25825869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150030 |
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