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The tumour suppressor CHD5 forms a NuRD-type chromatin remodelling complex

Eukaryotic gene expression is developmentally regulated, in part by chromatin remodelling, and its dysregulation has been linked to cancer. CHD5 (chromodomain helicase DNA-binding protein 5) is a tumour suppressor gene (TSG) that maps to a region of consistent deletion on 1p36.31 in neuroblastomas (...

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Bibliografski detalji
Izdano u:Biochem J
Glavni autori: Kolla, Venkatadri, Naraparaju, Koumudi, Zhuang, Tiangang, Higashi, Mayumi, Kolla, Sriharsha, Blobel, Gerd A., Brodeur, Garrett M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487910/
https://ncbi.nlm.nih.gov/pubmed/25825869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150030
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