Proteomic and Genetic Approaches Identify Syk as an AML Target

Cell-based screening can facilitate rapid identification of compounds inducing complex cellular phenotypes. Advancing a compound toward the clinic, however, generally requires identification of precise mechanisms of action. We previously found that epidermal growth factor receptor (EGFR) inhibitors...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hahn, Cynthia K., Berchuck, Jacob E., Ross, Kenneth N., Kakoza, Rose M., Clauser, Karl, Schinzel, Anna C., Ross, Linda, Galinsky, Ilene, Davis, Tina N., Silver, Serena J., Root, David E., Stone, Richard M., DeAngelo, Daniel J., Carroll, Martin, Hahn, William C., Carr, Steven A., Golub, Todd R., Kung, Andrew L., Stegmaier, Kimberly
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803063/
https://ncbi.nlm.nih.gov/pubmed/19800574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.08.018
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