Proteomic and Genetic Approaches Identify Syk as an AML Target

Cell-based screening can facilitate rapid identification of compounds inducing complex cellular phenotypes. Advancing a compound toward the clinic, however, generally requires identification of precise mechanisms of action. We previously found that epidermal growth factor receptor (EGFR) inhibitors...

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Detalhes bibliográficos
Main Authors: Hahn, Cynthia K., Berchuck, Jacob E., Ross, Kenneth N., Kakoza, Rose M., Clauser, Karl, Schinzel, Anna C., Ross, Linda, Galinsky, Ilene, Davis, Tina N., Silver, Serena J., Root, David E., Stone, Richard M., DeAngelo, Daniel J., Carroll, Martin, Hahn, William C., Carr, Steven A., Golub, Todd R., Kung, Andrew L., Stegmaier, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803063/
https://ncbi.nlm.nih.gov/pubmed/19800574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.08.018
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