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An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells

Regulation of expression of the CFTR gene is poorly understood. Elements within the basal promoter of the gene do not fully explain CFTR expression patterns, suggesting that cis-regulatory elements are located elsewhere, either within the locus or in adjacent chromatin. We previously mapped DNase I...

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Bibliografische gegevens
Hoofdauteurs: Blackledge, Neil P., Ott, Christopher J., Gillen, Austin E., Harris, Ann
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651798/
https://ncbi.nlm.nih.gov/pubmed/19129223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1056
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