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An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells

Regulation of expression of the CFTR gene is poorly understood. Elements within the basal promoter of the gene do not fully explain CFTR expression patterns, suggesting that cis-regulatory elements are located elsewhere, either within the locus or in adjacent chromatin. We previously mapped DNase I...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Blackledge, Neil P., Ott, Christopher J., Gillen, Austin E., Harris, Ann
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651798/
https://ncbi.nlm.nih.gov/pubmed/19129223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1056
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