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An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells
Regulation of expression of the CFTR gene is poorly understood. Elements within the basal promoter of the gene do not fully explain CFTR expression patterns, suggesting that cis-regulatory elements are located elsewhere, either within the locus or in adjacent chromatin. We previously mapped DNase I...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651798/ https://ncbi.nlm.nih.gov/pubmed/19129223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1056 |
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