Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. The cystic fibrosis transmembrane conductance regul...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Yang, Rui, Kerschner, Jenny L., Gosalia, Nehal, Neems, Daniel, Gorsic, Lidija K., Safi, Alexias, Crawford, Gregory E., Kosak, Steven T., Leir, Shih-Hsing, Harris, Ann
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838340/
https://ncbi.nlm.nih.gov/pubmed/26673704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1358
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