Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. The cystic fibrosis transmembrane conductance regul...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Yang, Rui, Kerschner, Jenny L., Gosalia, Nehal, Neems, Daniel, Gorsic, Lidija K., Safi, Alexias, Crawford, Gregory E., Kosak, Steven T., Leir, Shih-Hsing, Harris, Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838340/
https://ncbi.nlm.nih.gov/pubmed/26673704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1358
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