Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. The cystic fibrosis transmembrane conductance regul...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Yang, Rui, Kerschner, Jenny L., Gosalia, Nehal, Neems, Daniel, Gorsic, Lidija K., Safi, Alexias, Crawford, Gregory E., Kosak, Steven T., Leir, Shih-Hsing, Harris, Ann
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838340/
https://ncbi.nlm.nih.gov/pubmed/26673704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1358
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