Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus

Higher order chromatin structure establishes domains that organize the genome and coordinate gene expression. However, the molecular mechanisms controlling transcription of individual loci within a topological domain (TAD) are not fully understood. The cystic fibrosis transmembrane conductance regul...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Yang, Rui, Kerschner, Jenny L., Gosalia, Nehal, Neems, Daniel, Gorsic, Lidija K., Safi, Alexias, Crawford, Gregory E., Kosak, Steven T., Leir, Shih-Hsing, Harris, Ann
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
Onderwerpen:
Gene regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838340/
https://ncbi.nlm.nih.gov/pubmed/26673704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1358
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