Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells

The CFTR gene lies within an invariant topologically associated domain (TAD) demarcated by CTCF and cohesin, but shows cell-type specific control mechanisms utilizing different cis-regulatory elements (CRE) within the TAD. Within the respiratory epithelium, more than one cell type expresses CFTR and...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: NandyMazumdar, Monali, Yin, Shiyi, Paranjapye, Alekh, Kerschner, Jenny L, Swahn, Hannah, Ge, Alex, Leir, Shih-Hsing, Harris, Ann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Gene regulation, Chromatin and Epigenetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144911/
https://ncbi.nlm.nih.gov/pubmed/32095812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa089
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