Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells

The CFTR gene lies within an invariant topologically associated domain (TAD) demarcated by CTCF and cohesin, but shows cell-type specific control mechanisms utilizing different cis-regulatory elements (CRE) within the TAD. Within the respiratory epithelium, more than one cell type expresses CFTR and...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: NandyMazumdar, Monali, Yin, Shiyi, Paranjapye, Alekh, Kerschner, Jenny L, Swahn, Hannah, Ge, Alex, Leir, Shih-Hsing, Harris, Ann
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Gene regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144911/
https://ncbi.nlm.nih.gov/pubmed/32095812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa089
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki