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Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells

The CFTR gene lies within an invariant topologically associated domain (TAD) demarcated by CTCF and cohesin, but shows cell-type specific control mechanisms utilizing different cis-regulatory elements (CRE) within the TAD. Within the respiratory epithelium, more than one cell type expresses CFTR and...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: NandyMazumdar, Monali, Yin, Shiyi, Paranjapye, Alekh, Kerschner, Jenny L, Swahn, Hannah, Ge, Alex, Leir, Shih-Hsing, Harris, Ann
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144911/
https://ncbi.nlm.nih.gov/pubmed/32095812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa089
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