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Looping of upstream cis-regulatory elements is required for CFTR expression in human airway epithelial cells
The CFTR gene lies within an invariant topologically associated domain (TAD) demarcated by CTCF and cohesin, but shows cell-type specific control mechanisms utilizing different cis-regulatory elements (CRE) within the TAD. Within the respiratory epithelium, more than one cell type expresses CFTR and...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7144911/ https://ncbi.nlm.nih.gov/pubmed/32095812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa089 |
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