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CTCF mediates insulator function at the CFTR locus

Regulatory elements that lie outside the basal promoter of a gene may be revealed by local changes in chromatin structure and histone modifications. The promoter of the CFTR (cystic fibrosis transmembrane conductance regulator) gene is not responsible for its complex pattern of expression. To identi...

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Détails bibliographiques
Auteurs principaux: Blackledge, Neil P., Carter, Emma J., Evans, Joanne R., Lawson, Victoria, Rowntree, Rebecca K., Harris, Ann
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267356/
https://ncbi.nlm.nih.gov/pubmed/17696881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070429
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