The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins

par Lu, Gang, Middleton, Richard E., Sun, Huahang, Naniong, MarkVic, Ott, Christopher J., Mitsiades, Constantine S., Wong, Kwok-Kin, Bradner, James E., Kaelin, William G.
Publié 2013

Identification and characterization of Tyrosine Kinase Non-receptor 2 mutations in leukemia through integration of kinase inhibitor screening and genomic analysis

par Maxson, Julia E., Abel, Melissa L., Wang, Jinhua, Deng, Xianming, Reckel, Sina, Luty, Samuel B., Sun, Huahang, Gorenstein, Julie, Hughes, Seamus, Bottomly, Daniel, Wilmot, Beth, McWeeney, Shannon K., Radich, Jerald, Hantschel, Oliver, Middleton, Richard E, Gray, Nathanael S., Druker, Brian J., Tyner, Jeffrey W.
Publié dans Cancer Res (2015)

Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor

par Methot, Joey L., Hoffman, Dawn Mampreian, Witter, David J., Stanton, Matthew G., Harrington, Paul, Hamblett, Christopher, Siliphaivanh, Phieng, Wilson, Kevin, Hubbs, Jed, Heidebrecht, Richard, Kral, Astrid M., Ozerova, Nicole, Fleming, Judith C., Wang, Hongmei, Szewczak, Alexander A., Middleton, Richard E., Hughes, Bethany, Cruz, Jonathan C., Haines, Brian B., Chenard, Melissa, Kenific, Candia M., Harsch, Andreas, Secrist, J. Paul, Miller, Thomas A.
Publié 2014