Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2

Por van Bodegom, Diederik, Zhong, Jun, Kopp, Nadja, Dutta, Chaitali, Kim, Min-Sik, Bird, Liat, Weigert, Oliver, Tyner, Jeffrey, Pandey, Akhilesh, Yoda, Akinori, Weinstock, David M.
Publicado em 2012

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

Por Ott, Christopher J., Kopp, Nadja, Bird, Liat, Paranal, Ronald M., Qi, Jun, Bowman, Teresa, Rodig, Scott J., Kung, Andrew L., Bradner, James E., Weinstock, David M.
Publicado em 2012

Next-Generation cDNA Screening for Oncogene and Resistance Phenotypes

Por Shindoh, Nobuaki, Yoda, Akinori, Yoda, Yuka, Sullivan, Timothy J., Weigert, Oliver, Lane, Andrew A., Kopp, Nadja, Bird, Liat, Rodig, Scott J., Fox, Edward A., Weinstock, David M.
Publicado em 2012

Low Frequency Clonal Mutations Recoverable by Deep Sequencing in Patients with Aplastic Anemia

Por Lane, Andrew A., Odejide, Oreofe, Kopp, Nadja, Kim, Sunhee, Yoda, Akinori, Erlich, Rachel, Wagle, Nikhil, Abel, Gregory A., Rodig, Scott J., Antin, Joseph H., Weinstock, David M.
Publicado no Leukemia (2013)

Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

Por Melchardt, Thomas, Hufnagl, Clemens, Weinstock, David M., Kopp, Nadja, Neureiter, Daniel, Tränkenschuh, Wolfgang, Hackl, Hubert, Weiss, Lukas, Rinnerthaler, Gabriel, Hartmann, Tanja N., Greil, Richard, Weigert, Oliver, Egle, Alexander
Publicado no Oncotarget (2016)

BCL2 suppresses PARP1 function and non-apoptotic cell death

Por Dutta, Chaitali, Day, Tovah, Kopp, Nadja, van Bodegom, Diederik, Davids, Matthew S., Ryan, Jeremy, Bird, Liat, Kommajosyula, Naveen, Weigert, Oliver, Yoda, Akinori, Fung, Hua, Brown, Jennifer R., Shapiro, Geoffrey I., Letai, Anthony, Weinstock, David M.
Publicado em 2012

Targetable subsets of non-Hodgkin lymphoma in Malawi define therapeutic opportunities

Por Morgan, Elizabeth A., Sweeney, M. Patrick, Tomoka, Tamiwe, Kopp, Nadja, Gusenleitner, Daniel, Redd, Robert A., Carey, Christopher D., Masamba, Leo, Kamiza, Steve, Pinkus, Geraldine S., Neuberg, Donna S., Rodig, Scott J., Milner, Danny A., Weinstock, David M.
Publicado no Blood Adv (2016)

Molecular ontogeny of donor-derived follicular lymphomas occurring after hematopoietic cell transplantation

Por Weigert, Oliver, Kopp, Nadja, Lane, Andrew A., Yoda, Akinori, Dahlberg, Suzanne E., Neuberg, Donna, Bahar, Anita Y., Chapuy, Bjoern, Kutok, Jeff L., Longtine, Janina, Kuo, Frank C., Haley, Terry, Salois, Maura, Sullivan, Timothy J., Fisher, David C., Fox, Edward A., Rodig, Scott J., Antin, Joseph H., Weinstock, David M.
Publicado no Cancer Discov (2011)

A targeted mutational landscape of angioimmunoblastic T-cell lymphoma

Por Odejide, Oreofe, Weigert, Oliver, Lane, Andrew A., Toscano, Dan, Lunning, Matthew A., Kopp, Nadja, Kim, Sunhee, van Bodegom, Diederik, Bolla, Sudha, Schatz, Jonathan H., Teruya-Feldstein, Julie, Hochberg, Ephraim, Louissaint, Abner, Dorfman, David, Stevenson, Kristen, Rodig, Scott J., Piccaluga, Pier Paolo, Jacobsen, Eric, Pileri, Stefano A., Harris, Nancy L., Ferrero, Simone, Inghirami, Giorgio, Horwitz, Steven M., Weinstock, David M.
Publicado no Blood (2014)

Mutations in G protein beta subunits promote transformation and kinase inhibitor resistance

Por Yoda, Akinori, Adelmant, Guillaume, Tamburini, Jerome, Chapuy, Bjoern, Shindoh, Nobuaki, Yoda, Yuka, Weigert, Oliver, Kopp, Nadja, Wu, Shuo-Chieh, Kim, Sunhee S., Liu, Huiyun, Tivey, Trevor, Christie, Amanda L., Elpek, Kutlu G., Card, Joseph, Gritsman, Kira, Gotlib, Jason, Deininger, Michael W., Makishima, Hideki, Turley, Shannon J., Javidi-Sharifi, Nathalie, Maciejewski, Jaroslaw P., Jaiswal, Siddhartha, Ebert, Benjamin L., Rodig, Scott J., Tyner, Jeffrey W., Marto, Jarrod A., Weinstock, David M., Lane, Andrew A.
Publicado no Nat Med (2014)

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition

Por Weigert, Oliver, Lane, Andrew A., Bird, Liat, Kopp, Nadja, Chapuy, Bjoern, van Bodegom, Diederik, Toms, Angela V., Marubayashi, Sachie, Christie, Amanda L., McKeown, Michael, Paranal, Ronald M., Bradner, James E., Yoda, Akinori, Gaul, Christoph, Vangrevelinghe, Eric, Romanet, Vincent, Murakami, Masato, Tiedt, Ralph, Ebel, Nicolas, Evrot, Emeline, De Pover, Alain, Régnier, Catherine H., Erdmann, Dirk, Hofmann, Francesco, Eck, Michael J., Sallan, Stephen E., Levine, Ross L., Kung, Andrew L., Baffert, Fabienne, Radimerski, Thomas, Weinstock, David M.
Publicado em 2012

Activity of the type II JAK2 inhibitor CHZ868 in B-cell acute lymphoblastic leukemia

Por Wu, Shuo-Chieh, Li, Loretta S., Kopp, Nadja, Montero, Joan, Chapuy, Bjoern, Yoda, Akinori, Christie, Amanda L., Liu, Huiyun, Christodoulou, Alexandra, van Bodegom, Diederik, van der Zwet, Jordy, Layer, Jacob V., Tivey, Trevor, Lane, Andrew A., Ryan, Jeremy A., Ng, Samuel Y., DeAngelo, Daniel J., Stone, Richard M., Steensma, David, Wadleigh, Martha, Harris, Marian, Mandon, Emeline, Ebel, Nicolas, Andraos, Rita, Romanet, Vincent, Dölemeyer, Arno, Sterker, Dario, Zender, Michael, Rodig, Scott J., Murakami, Masato, Hofmann, Francesco, Kuo, Frank, Eck, Michael J., Silverman, Lewis B., Sallan, Stephen E., Letai, Anthony, Baffert, Fabienne, Vangrevelinghe, Eric, Radimerski, Thomas, Gaul, Christoph, Weinstock, David M.
Publicado no Cancer Cell (2015)

The Public Repository of Xenografts (ProXe) enables discovery and randomized phase II-like trials in mice

Por Townsend, Elizabeth C., Murakami, Mark A., Christodoulou, Alexandra, Christie, Amanda L., Köster, Johannes, DeSouza, Tiffany A., Morgan, Elizabeth A., Kallgren, Scott P., Liu, Huiyun, Wu, Shuo-Chieh, Plana, Olivia, Montero, Joan, Stevenson, Kristen E., Rao, Prakash, Vadhi, Raga, Andreeff, Michael, Armand, Philippe, Ballen, Karen K., Barzaghi-Rinaudo, Patrizia, Cahill, Sarah, Clark, Rachael A., Cooke, Vesselina G., Davids, Matthew S., DeAngelo, Daniel J., Dorfman, David M., Eaton, Hilary, Ebert, Benjamin L., Etchin, Julia, Firestone, Brant, Fisher, David C., Freedman, Arnold S., Galinsky, Ilene A., Gao, Hui, Garcia, Jacqueline S., Garnache-Ottou, Francine, Graubert, Timothy A., Gutierrez, Alejandro, Halilovic, Ensar, Harris, Marian H., Herbert, Zachary T., Horwitz, Steven M., Inghirami, Giorgio, Intlekoffer, Andrew M., Ito, Moriko, Izraeli, Shai, Jacobsen, Eric D., Jacobson, Caron A., Jeay, Sébastien, Jeremias, Irmela, Kelliher, Michelle A., Koch, Raphael, Konopleva, Marina, Kopp, Nadja, Kornblau, Steven M., Kung, Andrew L., Kupper, Thomas S., LaBoeuf, Nicole, LaCasce, Ann S., Lees, Emma, Li, Loretta S., Look, A. Thomas, Murakami, Masato, Muschen, Markus, Neuberg, Donna, Ng, Samuel Y., Odejide, Oreofe O., Orkin, Stuart H., Paquette, Rachel R., Place, Andrew E., Roderick, Justine E., Ryan, Jeremy A., Sallan, Stephen E., Shoji, Brent, Silverman, Lewis B., Soiffer, Robert J., Steensma, David P., Stegmaier, Kimberly, Stone, Richard M., Tamburini, Jerome, Thorner, Aaron R., van Hummelen, Paul, Wadleigh, Martha, Wiesmann, Marion, Weng, Andrew P., Wuerthner, Jens U., Williams, David A., Wollison, Bruce M., Lane, Andrew A., Letai, Anthony, Bertagnolli, Monica M., Ritz, Jerome, Brown, Myles, Long, Henry, Aster, Jon C., Shipp, Margaret A., Griffin, James D., Weinstock, David M.
Publicado no Cancer Cell (2016)