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Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

Little information is available about the role of certain mutations for clonal evolution and the clinical outcome during relapse in diffuse large B-cell lymphoma (DLBCL). Therefore, we analyzed formalin-fixed-paraffin-embedded tumor samples from first diagnosis, relapsed or refractory disease from 2...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Melchardt, Thomas, Hufnagl, Clemens, Weinstock, David M., Kopp, Nadja, Neureiter, Daniel, Tränkenschuh, Wolfgang, Hackl, Hubert, Weiss, Lukas, Rinnerthaler, Gabriel, Hartmann, Tanja N., Greil, Richard, Weigert, Oliver, Egle, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239491/
https://ncbi.nlm.nih.gov/pubmed/27285986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9860
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