Clonal evolution in relapsed and refractory diffuse large B-cell lymphoma is characterized by high dynamics of subclones

Little information is available about the role of certain mutations for clonal evolution and the clinical outcome during relapse in diffuse large B-cell lymphoma (DLBCL). Therefore, we analyzed formalin-fixed-paraffin-embedded tumor samples from first diagnosis, relapsed or refractory disease from 2...

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Vydáno v:Oncotarget
Hlavní autoři: Melchardt, Thomas, Hufnagl, Clemens, Weinstock, David M., Kopp, Nadja, Neureiter, Daniel, Tränkenschuh, Wolfgang, Hackl, Hubert, Weiss, Lukas, Rinnerthaler, Gabriel, Hartmann, Tanja N., Greil, Richard, Weigert, Oliver, Egle, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239491/
https://ncbi.nlm.nih.gov/pubmed/27285986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9860
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