Functional consequences of EpCam mutation in mice and men

Bằng Mueller, James L., McGeough, Matthew D., Peña, Carla A., Sivagnanam, Mamata
Được phát hành 2013

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

Bằng Brydges, Susannah D., Broderick, Lori, McGeough, Matthew D., Pena, Carla A., Mueller, James L., Hoffman, Hal M.
Được phát hành 2013

Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

Bằng Johnson, Jennifer L., Ramadass, Mahalakshmi, Haimovich, Ariela, McGeough, Matthew D., Zhang, Jinzhong, Hoffman, Hal M., Catz, Sergio D.
Xuất bản năm Front Cell Infect Microbiol (2017)

Interleukin-6 is a Marker of Inflammation with No Direct Role in Inflammasome-Mediated Mouse Models()

Bằng McGeough, Matthew D., Pena, Carla A., Mueller, James L., Pociask, Derek A., Broderick, Lori, Hoffman, Hal M., Brydges, Susannah D.
Được phát hành 2012

Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction

Bằng Kozan, Philip A., McGeough, Matthew D., Peña, Carla A., Mueller, James L., Barrett, Kim E., Marchelletta, Ronald R., Sivagnanam, Mamata
Xuất bản năm J Mol Med (Berl) (2014)

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis

Bằng Wree, Alexander, Eguchi, Akiko, McGeough, Matthew D., Pena, Carla A., Johnson, Casey D., Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
Được phát hành 2014

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

Bằng Wree, Alexander, McGeough, Matthew D., Peña, Carla A., Schlattjan, Martin, Li, Hongying, Inzaugarat, Maria Eugenia, Messer, Karen, Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
Xuất bản năm J Mol Med (Berl) (2014)

Enteroids expressing a disease-associated mutant of EpCAM are a model for congenital tufting enteropathy

Bằng Das, Barun, Okamoto, Kevin, Rabalais, John, Kozan, Philip A., Marchelletta, Ronald R., McGeough, Matthew D., Durali, Nassim, Go, Maria, Barrett, Kim E., Das, Soumita, Sivagnanam, Mamata
Xuất bản năm Am J Physiol Gastrointest Liver Physiol (2019)

TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies

Bằng McGeough, Matthew D., Wree, Alexander, Inzaugarat, Maria E., Haimovich, Ariela, Johnson, Casey D., Peña, Carla A., Goldbach-Mansky, Raphaela, Broderick, Lori, Feldstein, Ariel E., Hoffman, Hal M.
Xuất bản năm J Clin Invest (2017)

NLRP3 inflammasome activation in hepatic stellate cells induces murine liver fibrosis

Bằng Inzaugarat, Maria Eugenia, Johnson, Casey D., Holtmann, Theresa Maria, McGeough, Matthew D., Trautwein, Christian, Papouchado, Bettina G., Schwabe, Robert, Hoffman, Hal M., Wree, Alexander, Feldstein, Ariel E.
Xuất bản năm Hepatology (2019)

Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart

Bằng Toldo, Stefano, Mezzaroma, Eleonora, McGeough, Matthew D., Peña, Carla A., Marchetti, Carlo, Sonnino, Chiara, Van Tassell, Benjamin W., Salloum, Fadi N., Voelkel, Norbert F., Hoffman, Hal M., Abbate, Antonio
Xuất bản năm Cardiovasc Res (2015)

Targeting epithelial ORMDL3 increases, rather than reduces, airway responsiveness and is associated with increased sphingosine-1-phosphate

Bằng Miller, Marina, Tam, Arvin B., Mueller, James L, Rosenthal, Peter, Beppu, Andrew, Gordillo, Ruth, McGeough, Matthew D., Vuong, Christine, Doherty, Taylor A., Hoffman, Hal M., Niwa, Maho, Broide, David H.
Xuất bản năm J Immunol (2017)

NLRP3 inflammasome driven liver injury and fibrosis: roles of IL- 17 and TNF

Bằng Wree, Alexander, McGeough, Matthew D., Inzaugarat, Maria Eugenia, Eguchi, Akiko, Schuster, Susanne, Johnson, Casey D., Peña, Carla A., Geisler, Lukas J., Papouchado, Bettina G, Hoffman, Hal M., Feldstein, Ariel E.
Xuất bản năm Hepatology (2017)

ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma

Bằng Miller, Marina, Rosenthal, Peter, Beppu, Andrew, Mueller, James L, Hoffman, Hal M., Tam, Arvin B., Doherty, Taylor A., McGeough, Matthew D., Pena, Carla A, Suzukawa, Maho, Niwa, Maho, Broide, David H.
Được phát hành 2014

GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation

Bằng Das, Sudipta, Miller, Marina, Beppu, Andrew K., Mueller, James, McGeough, Matthew D., Vuong, Christine, Karta, Maya R., Rosenthal, Peter, Chouiali, Fazila, Doherty, Taylor A., Kurten, Richard C., Hamid, Qutayba, Hoffman, Hal M., Broide, David H.
Xuất bản năm Proc Natl Acad Sci U S A (2016)

ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model

Bằng Schuster-Gaul, Susanne, Geisler, Lukas Jonathan, McGeough, Matthew D., Johnson, Casey D., Zagorska, Anna, Li, Li, Wree, Alexander, Barry, Vivian, Mikaelian, Igor, Jih, Lily J., Papouchado, Bettina G., Budas, Grant, Hoffman, Hal M., Feldstein, Ariel E.
Xuất bản năm JCI Insight (2020)

NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms

Bằng Qu, Chao, Bonar, Sheri L., Hickman-Brecks, Cynthia L., Abu-Amer, Samer, McGeough, Matthew D., Peña, Carla A., Broderick, Lori, Yang, Chang, Grimston, Susan K., Kading, Jacqueline, Abu-Amer, Yousef, Novack, Deborah V., Hoffman, Hal M., Civitelli, Roberto, Mbalaviele, Gabriel
Xuất bản năm FASEB J (2015)

Animal Models of Inflammasomopathies Reveal Roles for Innate but not Adaptive Immunity

Bằng Brydges, Susannah D, Mueller, James L, McGeough, Matthew D, Pena, Carla A, Misaghi, Amirhossein, Gandhi, Chhavi, Putnam, Chris D, Boyle, David L, Firestein, Gary S, Horner, Anthony A, Soroosh, Pejman, Watford, Wendy T, O’Shea, John J, Kastner, Daniel L, Hoffman, Hal M
Được phát hành 2009

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

Bằng Bonar, Sheri L., Brydges, Susannah D., Mueller, James L., McGeough, Matthew D., Pena, Carla, Chen, Debbie, Grimston, Susan K., Hickman-Brecks, Cynthia L., Ravindran, Soumya, McAlinden, Audrey, Novack, Deborah V., Kastner, Daniel L., Civitelli, Roberto, Hoffman, Hal M., Mbalaviele, Gabriel
Được phát hành 2012

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

Bằng Gaul, Susanne, Leszczynska, Aleksandra, Alegre, Fernando, Kaufmann, Benedikt, Johnson, Casey D., Adams, Leon A., Wree, Alexander, Damm, Georg, Seehofer, Daniel, Calvente, Carolina J., Povero, Davide, Kisseleva, Tatiana, Eguchi, Akiko, McGeough, Matthew D., Hoffman, Hal M., Pelegrin, Pablo, Laufs, Ulrich, Feldstein, Ariel E.
Xuất bản năm J Hepatol (2020)