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Independent roles of the priming and the triggering of the NLRP3 inflammasome in the heart
AIMS: The NLRP3 inflammasome is activated in the ischaemic heart promoting caspase-1 activation, inflammation, and cell death. Ischaemic injury establishes both a priming signal (transcription of inflammasome components) and a trigger (NLRP3 activation). Whether NLRP3 activation, without priming, in...
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Publicado no: | Cardiovasc Res |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357795/ https://ncbi.nlm.nih.gov/pubmed/25524927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu259 |
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