Therapy of autoinflammatory syndromes

Por Hoffman, Hal M.
Publicado no J Allergy Clin Immunol (2009)

Inflammasome and IL-1β-Mediated Disorders

Por Hoffman, Hal M., Wanderer, Alan A.
Publicado em 2010

Genetic and Molecular Basis of Inflammasome-mediated Disease

Por Hoffman, Hal M., Brydges, Susannah D.
Publicado em 2011

Autoinflammation: translating mechanism to therapy

Por Doherty, Taylor A., Brydges, Susannah D., Hoffman, Hal M.
Publicado em 2011

Familial Atypical Cold Urticaria: Description of a New Hereditary Disease

Por Gandhi, Chhavi, Healy, Chris, Wanderer, Alan A., Hoffman, Hal M.
Publicado em 2009

Association between celiac sprue and cryopyrin associated autoinflammatory disorders: a case report

Por Shaker, Marcus, Edwards, Susan, Chionuma, Henry, Shamansky, Eric, Hoffman, Hal M
Publicado em 2007

Prolonged urticaria and fever in a toddler

Por Broderick, Lori, Tremoulet, Adriana H., Burns, Jane C., Hoffman, Hal M.
Publicado em 2012

Recurrent Fever Syndromes in Patients After Recovery From Kawasaki Syndrome

Por Broderick, Lori, Tremoulet, Adriana H., Burns, Jane C., Bastian, John F., Hoffman, Hal M.
Publicado em 2011

Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy

Por Yu, Jiujiu, Nagasu, Hajime, Murakami, Tomohiko, Hoang, Hai, Broderick, Lori, Hoffman, Hal M., Horng, Tiffany
Publicado em 2014

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

Por Hoffman, Hal M., Mueller, James L., Broide, David H., Wanderer, Alan A., Kolodner, Richard D.
Publicado no Nat Genet (2001)

The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media

Por Kurabi, Arwa, Lee, Jasmine, Wong, Chelsea, Pak, Kwang, Hoffman, Hal M, Ryan, Allen F, Wasserman, Stephen I
Publicado no Innate Immun (2014)

Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

Por Brydges, Susannah D., Broderick, Lori, McGeough, Matthew D., Pena, Carla A., Mueller, James L., Hoffman, Hal M.
Publicado em 2013

Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity

Por Liu, George Y., Essex, Anthony, Buchanan, John T., Datta, Vivekanand, Hoffman, Hal M., Bastian, John F., Fierer, Joshua, Nizet, Victor
Publicado em 2005

Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity

Por Pollard, K. Michael, Hultman, Per, Toomey, Christopher B., Cauvi, David M., Hoffman, Hal M., Hamel, John C., Kono, Dwight H.
Publicado em 2012

A Group A Streptococcus ADP-Ribosyltransferase Toxin Stimulates a Protective Interleukin 1β-Dependent Macrophage Immune Response

Por Lin, Ann E., Beasley, Federico C., Keller, Nadia, Hollands, Andrew, Urbano, Rodolfo, Troemel, Emily R., Hoffman, Hal M., Nizet, Victor
Publicado no mBio (2015)

Interleukin-6 is a Marker of Inflammation with No Direct Role in Inflammasome-Mediated Mouse Models()

Por McGeough, Matthew D., Pena, Carla A., Mueller, James L., Pociask, Derek A., Broderick, Lori, Hoffman, Hal M., Brydges, Susannah D.
Publicado em 2012

Monocytes from familial cold autoinflammatory syndrome patients are activated by mild hypothermia

Por Rosengren, Sanna, Mueller, James L., Anderson, Justin P., Niehaus, Brian L., Misaghi, Amirhossein, Anderson, Scott, Boyle, David L., Hoffman, Hal M.
Publicado no J Allergy Clin Immunol (2007)

Structural, expression, and evolutionary analysis of mouse CIAS1(,)

Por Anderson, Justin P., Mueller, James L., Rosengren, Sanna, Boyle, David L., Schaner, Philip, Cannon, Steven B., Goodyear, Carl S., Hoffman, Hal M.
Publicado no Gene (2004)

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis

Por Wree, Alexander, Eguchi, Akiko, McGeough, Matthew D., Pena, Carla A., Johnson, Casey D., Canbay, Ali, Hoffman, Hal M., Feldstein, Ariel E.
Publicado em 2014

Interleukin-1β and Inflammasome Activity Link Inflammation to Abnormal Fetal Airway Development

Por Stouch, Ashley N., McCoy, Alyssa M., Greer, Rachel M., Lakhdari, Omar, Yull, Fiona E., Blackwell, Timothy S., Hoffman, Hal M., Prince, Lawrence S.
Publicado no J Immunol (2016)