Definition of IFN-γ-related pathways critical for chemically-induced systemic autoimmunity

IFN-γ is essential for idiopathic and murine mercury-induced systemic autoimmunity (mHgIA), and heterozygous IFN-γ(+/−) mice also exhibit reduced disease. This suggests that blocking specific IFN-γ-related pathways that may only partially inhibit IFN-γ production or function will also suppress autoi...

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Autori principali: Pollard, K. Michael, Hultman, Per, Toomey, Christopher B., Cauvi, David M., Hoffman, Hal M., Hamel, John C., Kono, Dwight H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570757/
https://ncbi.nlm.nih.gov/pubmed/22578563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.04.003
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