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β(2)-Microglobulin is Required for the Full Expression of Xenobiotic-Induced Systemic Autoimmunity
Mercury exposure in both humans and mice is associated with features of systemic autoimmunity. Murine HgCl(2)-induced autoimmunity (mHgIA) requires MHC Class II, CD4(+) T-cells, co-stimulatory molecules, and interferon-γ (IFNγ), similar to spontaneous models of systemic lupus erythematosus (SLE). β(...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257888/ https://ncbi.nlm.nih.gov/pubmed/21793797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1547691X.2011.583614 |
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